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Master of Sciences Thesis Bioinformatics f|m|d

Your Role:

  • In your Master of Sciences thesis project you will develop computational analysis methods to automatically identify and characterize neuronal cells in multiparametric immunofluorescence image data.
  • You will improve image processing tools
  • To characterize neuronal developmental stages you will apply data reduction and machine learning on a knowledge database of marker profiles and update the content of the database
  • With the development of novel visualization and reporting tools you will make your analysis pipelines and database queries available to your colleagues and the scientific community

Your Profile:

  • You approach a MSc. degree or equivalent in Bioinformatics or Biology with major in Bioinformatics
  • You are proficient in programming R. Experience in Json/Bson, Python, Java and/or Linux shell scripting is of advantage
  • Ideally you have experience with machine learning and the establishment, maintenance, and queries of noSQL databases (i.e., MongoDB)
  • You are an enthusiastic team player and apply your scientific knowhow to solve problems in a goal oriented and creative manner
  • Fluency in German and English will help you communicate with your colleagues

Further Information:

The differentiation of pluripotent stem cells (PSC) into neuronal cell types opens a potential route towards therapeutic treatment of neurodegenerative diseases such as Parkinson´s Disease. Differentiations from stem cells result in a culture of mixed cell types that could limit the success of the therapeutic treatment. Therefore, novel multiparametric immunofluorescent staining technology has been applied to better characterize these cell types. In this MSc thesis project the different neuronal cell types will be characterized by automated image analysis implementing improved image processing, machine learning, and visualization tools for multiparametric data.

Ihr Ansprechpartner

Benjamin Malik
Tel.: +49 2204 8306 2430

Fortschritt entsteht aus Inspiration und Neugier. Seit 30 Jahren entwickelt Miltenyi Biotec Produkte und Services, die in Grundlagenforschung, translationaler Forschung und Zelltherapie eingesetzt werden. Heute sind wir ein weltweites Team aus über 2.300 Wissenschaftlern, Medizinern, Ingenieuren, Vertrieblern und zahlreichen weiteren Spezialisten. Bei uns werden aus neuen Ideen einzigartige Produkte. Gemeinsam treiben wir mit großer Leidenschaft den biomedizinischen Fortschritt zur Heilung schwerer Erkrankungen voran.

Miltenyi Biotec GmbH
Human Resources
Friedrich-Ebert-Strasse 68
51429 Bergisch Gladbach Germany