Your role:
- Establishment of several xenograft models with different stroma thicknesses
- Investigation of various pharmacological pretreatment schemes that can thin the tumor stroma
- Development of CAR constructs and functional CAR T cells for the identified target structures and in vivo testing in combination with the best pharmacological pretreatment scheme
- Transfer pharmacologically derived information into a biological manipulation of CAR T cells
- Active expansion of scientific cooperation in immunotherapy, at least one first-author publication is expected